Global Health EDCTP3 Joint Undertaking (EDCTP3) - 2025 calls

Research, Internationalization

What?

The Global Health EDCTP3 Joint Undertaking (GH EDCTP3 JU) is a partnership between the European Union and the European and Developing Countries Clinical Trials Partnership (EDCTP) Association whose members are several EU Member States and Associated countries and several African countries.

Activities funded under the 2025 Work Programme calls for proposals of the Global Health EDCTP3 JU should contribute to:
  • Reduce the individual, social, and economic burdens of infectious diseases in sub-Saharan Africa (SSA) through the development and uptake of new or improved interventions.
  • Increase health security in SSA and globally by reducing the risk of outbreaks and pandemics and enhancing national and regional capacity to address antimicrobial resistance.
  • Progressing towards the achievement of SDG3 ‘Ensure healthy lives and promote well-being for all at all ages’ in SSA countries
The work programme includes four calls for proposals covering seven topics, with a total budget of €214 million. These calls are opening in January and have submission deadlines for the first (short proposal) and second (full proposal) stage in March and September, respectively. For these calls, the legal and financial provisions as described in Annex G of the Horizon Europe Work Programme General Annexes apply.
  • HORIZON-JU-GH-EDCTP3-2025-01-TB-01-two-stage (RIA): Global collaboration action for the development of vaccines for reducing the disease burden of Tuberculosis in sub-Saharan Africa
  • HORIZON-JU-GH-EDCTP3-2025-01-MALARIA-02-two-stage (RIA): Global collaboration action for research on existing Malaria therapeutics and clinical development of new antimalarial candidates
  • HORIZON-JU-GH-EDCTP3-2025-01-NTD-03-two-stage (RIA): Accelerating the development of prophylactic vaccines against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa
  • HORIZON-JU-GH-EDCTP3-2025-02-FELLOWSHIP-01-two-stage (CSA): Global Health EDCTP3 and contributing partners funded Strategic Training Hubs for Fellowships in Public Health covering Biostatistics, Epidemiology and Modelling
  • HORIZON-JU-GH-EDCTP3-2025-03-NETWORKS-01-two-stage (CSA): Global collaborative action for strengthening the Regional Networks of Excellence and Epidemic Preparedness Consortia
  • HORIZON-JU-GH-EDCTP3-2025-04-CH-01-two-stage (RIA): Global collaborative action tackling diarrhoeal diseases in the context of climate and health
  • HORIZON-JU-GH-EDCTP3-2025-04-ACCESS-02-two-stage (RIA): Transformative Innovations in global health
  • HORIZON-JU-GH-EDCTP3-2025-05-AFRICA-01-IBA: Support for the Africa office of the EDCTP Association

Who?

Applicants established in a Member States of the European Union are eligible for funding, following standard Horizon Europe eligibility rules (General Annex B). The complete list of eligible countries is available in the work programme, p. 49.

Consortia should include as beneficiaries:
  • At least three legal entities independent from each other and each established in a different country
  • At least one independent legal entity established in a Member State, or in an associated country to Horizon Europe that is a member of the EDCTP Association
  • At least one independent legal entity established in a sub-Saharan African country that is a member of the EDCTP Association
For the two CSA topics, the EDCTP Association is obligatorily part of the consortium as coordinator. Here, the EDCTP Association must not be counted as one of the three independent legal entities necessary to ensure the eligibility of the consortium composition.

Application?

Evaluation scores will be awarded for the criteria as described in General Annex D of the Horizon Europe Work Programme. For full applications, each criterion will be scored out of 5. The threshold for criteria Excellence and Impact will be 4, and 3 for criterion Quality and Efficiency of the implementation. The overall threshold, applying to the sum of the three individual scores, will be 12. Additionally, call specific aspects can be taken into consideration during the evaluation of second-stage proposals. Proposals that pass the individual threshold and the overall threshold will be considered for funding, within the limits of the available call budget. Other proposals will be rejected. For the first stage of the two-stage evaluation, the scores and weighting as indicated in Annex D of the General Annexes of the Horizon Europe work programme 2023-2025 apply.

Regulations?

If the coordinator is not established in a country in SSA, the designation of a scientific project leader established in a SSA country member of the EDCTP Association with the roles as described below is mandatory. A work package on ‘scientific project leadership’ must be included in the proposals and budget needs to be provided for this activity. The scientific project leader oversees the project scientific governance and leadership. For this purpose, proposals must include a work package where the details of scientific project leadership are laid down.

More information?

Info days on the new work programme are expected to be organised early 2025.

Deadline

01.03.2025

Contact Hasselt University?

E-mail ward.ceunen@uhasselt.be

Tel. +3211268945

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