Title
New alternative carcinogenic prediction assay using flatworm stem cell proliferation patterns. (Research)
Abstract
Flatworms are promising model organisms for cancer research because of their experimentally accessible stem cells and remarkable regeneration capacity. Previously, we developed a non-mammalian, in vivo carcinogenic assay, which has the potential to bridge the gap between in vitro /cellular assays and mammalian models in carcinogenicity screenings. In the 'proof of concept'-project, we will validate the assay by increasing the number of tested compounds. Target markets and valorization strategies will be explored to in function of further implementation of our stem-cell-based assay.
Period of project
01 March 2017 - 30 June 2018