Project R-15259

Aging Screen: Implementation of a state-of-the-art multiplex screening platform on the Health Campus for measuring both cellular aging and disease-specific markers. (Research)

Globally, we are witnessing a drastic increase in age-related chronic conditions, such as cardiovascular diseases, cancer, Alzheimer's, osteoporosis, and rheumatoid arthritis. Therefore, R&D in gerontology, the science that studies aging, is more important than ever. This is reflected in the growing investments in the development of new or repurposed drugs that target the mechanisms of aging. In the AGING SCREEN project, Hasselt University is developing a pharmacological screening platform that will map aging in tissues and cells. Preclinical research at UHasselt already routinely measures multiple characteristics of aging. During the project, the aim is to expand expertise in these analyses by developing a preclinical multiplex screening platform that encompasses all aspects of aging at the cellular level. Furthermore, we aim to create an innovative platform capable of simultaneously measuring not only the characteristics of cellular aging but also disease-specific markers, all within the same platform. In addition to UHasselt's own research, this platform will be made available to knowledge centers studying age-related diseases and to companies developing medicines to prevent or treat aging-related diseases. Companies will be able to use this platform to determine which products effectively target the hallmarks of aging. This state-of-the-art platform is crucial for strengthening the innovation potential in our region. It will enable new collaborations and attract companies focusing on aging and age-related diseases to our ecosystem. This application is part of a larger, approved SALKturbo initiative ("Older and Wiser: Limburg as a knowledge hub for innovation in aging") through which UHasselt aims to ensure that Limburg is top of mind when people think of aging research. By investing in research and development in gerontology, our region can contribute to the development of new treatments and services for the growing group of older individuals in our society.

01 October 2024 - 01 October 2027