Project R-1993

Underlying mechanisms of neuroplasticity and motor control: Modulation of neuroplasticity in the development of novel rehabilitation strategies in neurodegenerative diseases (Research)

The main goal of this research program is to acquire fundamental understanding of the underlying mechanisms involved in functional and structural neuroplasticity. Understanding these mechanisms is important in the development of scientifically-based therapies in neurorehabilitation. This project specifically investigates the carry-over effects of proprioceptive and active exercise therapy on cortical excitability and functionality in healthy individuals and in patients with neurological diseases (Multiple Sclerosis, Aging, Parkinson, etc.). More detailed, we are focusing on improving tactile sensitivity and motor function in patients suffering from functional loss in the upper limbs. To accomplish these interests, we use different forms of non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), as well as peripheral nerve stimulation (TENS) and behavioral tasks.

01 October 2008 - 30 September 2010