Expertise

At the AOMC, all microscopes are capable of imaging both live and fixed samples. However, each system (technique) has its own set of advantages and disadvantages, making them more or less suited for different applications. Every microscope is equipped with an enclosing incubator and stage inserts that allow precise temperature and pH control for optimal sample conditions.

The diffraction-limited nature of light microscopy does not always provide sufficient resolution to see all desired details. At the AOMC, multiple techniques are available to record images with improved (super) resolution. Each of these methods has its own set of advantages and disadvantages, so they can be matched to almost any research question.

It is not always required to label a sample with fluorophores in order to visualize it. Several structures and components can be imaged using label-free imaging techniques.

Biomolecules hide a wealth of information in the way they move about! We specialize in fluctuation spectroscopy methods for quantifying biomolecular diffusion and binding processes.

Biomolecules hide a wealth of information in the way they move about! We specialize in single-molecule methods for quantifying biomolecular structure and conformational dynamics.

Fluorophores hide a wealth of information in the way they fluoresce! We specialize in time-resolved methods for quantifying fluorescence lifetimes and anisotropy.

Explore molecular motion beyond Brownian diffusion using array-based confocal detection.